L’engouement de l’utilisation du double blocage a vu le jour au début des années 2000 lorsque les études RENAAL et IDNT (parues dans le NEJM en 2001) ont montré que le blocage simple permettait de réduire le risque d’insuffisance rénale terminale chez les patients diabétiques de type 2 insuffisants rénaux protéinuriques. Ce blocage était bénéfique…
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